Method of using oxygen to eliminate carbon dioxide poisoning in aerobic fermentation
AssigneePraxair Technology, Inc.
InventorAlan Tat Yan Cheng
Life of this patent
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Abstract
A method for carrying out fermentation comprising the steps of providing a vessel with elevated pressure up to 25 atm which contains a broth comprising a constituent capable of undergoing fermentation, lowering the vessel pressure within the vessel to lower the equilibrium oxygen partial pressure, adding pure oxygen into the vessel to raise the equilibrium oxygen partial pressure therein, and utilizing the pure oxygen to carry out the fermentation of the constituent.
Claims14
A method for carrying out fermentation comprising:
- a. providing a vessel with a pressure up to 25 atmospheres which contains a broth comprising a constituent capable of undergoing fermentation and a biomass capable of fermenting the constituent;
- b. lowering the vessel pressure within said vessel to lower the equilibrium oxygen partial pressure and the dissolved carbon dioxide concentration in the vessel proportional to said lowered vessel pressure wherein said vessel pressure is lowered between 25 atmospheres and about 1 atmosphere;
- c. adding pure oxygen into said vessel to raise said equilibrium oxygen partial pressure therein;
- and
- d. utilizing said pure oxygen to carry out the fermentation of said constituent.
A method for increasing the biomass concentration in carrying out fermentation comprising:
- a. providing a vessel with a pressure up to 25 atmospheres which contains a broth comprising a constituent capable of undergoing fermentation and a biomass capable of fermenting the constituent;
- b. lowering the vessel pressure within said vessel to lower the equilibrium oxygen partial pressure and the dissolved carbon dioxide concentration in the vessel proportional to said lowered vessel pressure wherein said vessel pressure is lowered between 25 atmospheres and about 1 atmosphere;
- c. adding pure oxygen into said vessel to raise said equilibrium oxygen partial pressure therein;
- and
- d. utilizing said pure oxygen to carry out the fermentation of said constituent.
Dependencies are inferred from the claim text.