Immortalized avian cell lines
AssigneeInstitut Naltional de la Recherche Agronomiqe
InventorsJean-François Bouquet, Miloud Benchaïbi, Jacques Samarut, Philippe Desmettre
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Abstract
The invention features non-transformant immortal avian cells, in particular derived from avian tissues, i.e. other than blood or haemotopoietic cells, particularly fibroblasts and epithelial cells, for instance of embryos. The avian cells are immortalized by the SV40 T+t gene in the dependence of the MTI promoter. In particular they integrate the pDAMT vector.
Claims14
Immortal, but untransformed, avian embryonic fibroblast cells and their progeny, wherein these cells comprise in their genome, the SV 40 T+t gene.
Immortal, untransformed avian cell line TDF-2A, which is deposited in the CNCM (Collection Nationale de Cultures de Microorganismes de l'Institut pasteur (Pasteur Institute national Collection of Microorganism Cultures)) under reference number 1-1712.
Immortal, but untransformed, avian embryonic fibroblast cells and their progeny, wherein the cells comprise in their genome a vector consisting essentially of an immortalization gene, a promoter of this gene and LTR sequences.
Dependencies are inferred from the claim text.