Antimicrobial oral composition and method of use
OwnerJoseph Alan Sasson, Riccardo Panicucciinventors
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Abstract
This invention provides a liquid antimicrobial composition that is particularly useful as a mouthwash for treating or reducing the risk of dental disease. The composition is prepared by mixing a first solution comprising a water soluble metal chlorite compound with a second solution comprising sodium persulfate and hydrogen peroxide. The resulting composition, containing chlorine dioxide, is preferably used at the time of preparation by applying the composition to the locus where treatment is desired.
Claims12
A method of treating or reducing the risk of a microbial infection comprising the steps of:
- (a) providing a first solution comprising a water-soluble chlorite compound, said chlorite compound present at a concentration in the range of about 0.1 to 0.5% by weight, and said first solution having an alkaline pH;
- (b) providing a second solution comprising sodium persulfate and hydrogen peroxide, said sodium persulfate present at a concentration in the range of about 1.0 to 10% by weight, said hydrogen peroxide present at a concentration in the range of about 0.3 to 1.5% by weight, and said second solution having a pH in the range of about 1 to 6;
- (c) mixing the first solution and the second solution to provide an antimicrobial composition, wherein said composition has a pH below 7;
- and
- (d) applying the composition of step (c) to the locus of the microbial infection.
A method of treating or reducing the risk of dental disease comprising the steps of:
- (a) a first liquid component comprising a water-soluble chlorite compound, said chlorite compound present at a concentration in the range of about 0.1 to 0.5% by weight, and said first component having an alkaline pH;
- (b) a second liquid component comprising a second solution comprising sodium persulfate and hydrogen peroxide, said sodium persulfate present at a concentration in the range of about 1.0 to 10% by weight, said hydrogen peroxide present at a concentration in the range of about 0.3 to 1.5% by weight, and said second component having a pH in the range of about 1 to 6;
- (c) mixing the first solution and the second solution to provide an antimicrobial composition, wherein said composition has a pH below 7;
- and
- (d) applying the composition of step (c) to the locus of the microbial infection.
A method of treating or reducing the risk of a microbial infection comprising the step of applying to the locus where treatment or prevention is desired, an antimicrobial composition comprising (a) about 1-100 ppm chlorine dioxide;
- (b) about 0.5-5% by weight of sodium persulfate;
- (c) about 0.15-0.75% by weight of hydrogen peroxide;
- and (d) about 0.05 to 0.5% by weight of a chlorite, said composition having a pH below 7.
A method for treating or reducing the risk of a microbial infection comprising the step of applying an antimicrobial composition having a pH below about 7 to the locus or surface of the microbial infection, wherein said composition is prepared by mixing a first solution with a second solution, the first solution comprising about 0.05 to 0.25% of a water soluble metal chlorite and the second solution comprising about 0.5 to 5% sodium persulfate and about 0.15 to 0.75% hydrogen peroxide, wherein the quantities of chlorite, sodium persulfate and hydrogen peroxide are based on the weight of the antimicrobial composition.
A dental mouthwash product comprising:
- (a) a first liquid component comprising a water-soluble chlorite compound, said chlorite compound present at a concentration in the range of about 1.0 to 0.5% by weight, and said second solution having an alkaline pH;
- (b) a second liquid component comprising a second solution comprising sodium persulfate and hydrogen peroxide, said sodium persulfate present at a concentration in the range of about 1.0 to 10% by weight, said hydrogen peroxide present at a concentration in the range of about 0.3 to 1.5% by weight, and said second solution having a pH in the range of about 1 to 6;
- and
- (c) a suitable container that separately houses the first liquid component and the second liquid component.
Dependencies are inferred from the claim text.