Method for transdermal application of active substances at high constant dosage

A method of transdermal treatment of a patient suffering from an illness or painful conditions or a patient with drug or narcotics dependency by administering to said patient transdermal therapeutic systems comprising a therapeutically effective active substance in order to ensure a blood plasma concentration of the active substance which is approximately constant over a useful application period, which comprises applying to the patient said transdermal therapeutic system in at least one treatment cycle, each cycle comprising several days and comprising the following steps:

• (a) application of at least one transdermal therapeutic system, comprising the active substance, with a defined application period of several days;
• (b) application of at least one further transdermal therapeutic system, comprising the active substance, before the expiry of half the period of time within which the active substance content of the initially applied transdermal therapeutic system(s) is substantially exhausted;
• (c) removal of the initially applied transdermal therapeutic system(s) when its (their) active substance contents is (are) substantially exhausted.