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US 6,280,737 B1Granted
Harpagoside-enriched extract from harpagophytum procumbens and processes for producing same
AssigneeDr. Willmar Schwabe GmbH & Co.
InventorsKarl-Heinz Stumpf, Hermann Jaggy, Rainer Oschmann, Egon Koch, Thomas Simmet
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Abstract
The disclosure relates to extracts from Harpagophytum procumbens with a high harpagoside content, to processes for producing them, such extracts containing no components capable of stimulating the synthesis of thromboxane B2 and cysteinylleucotrienes, and to pharmaceutical compositions containing such extracts.
Claims9
A drug extract from Harpagophytum procumbens obtainable by the steps of:
- a) extracting the drug from Harpagophytum procumbens with water or a mixture of ethanol and water,
- b) concentrating the resulting extract;
- c) stirring the concentrate obtained at temperatures of 5 to 25° C. with a neat aliphatic alcohol having 1-4 carbon atoms or an aliphatic ketone having 3 to 4 carbon atoms or the mixtures thereof;
- and
- d) separating the insoluble fraction from the obtained soluble fraction, wherein the soluble fraction is the drug extract and has a strongly reduced content in ingredients having stimulatory effects on the synthesis of thromboxane B2 and cysteinyl-leucotrienes.
2 more elements
Dependencies are inferred from the claim text.