Method of filling a drug capsule and article produced thereby

A filled and sealed drug-containing article for attachment to a needleless injector power source, which comprises a needleless injector capsule defining a chamber having a drug in liquid form therein, the capsule having an orifice through a wall thereof, a seal carrier having therein a seal in which is formed an orifice communication with the capsule orifice, the seal being in sealing contact with the capsule wall around the orifice in the capsule wall, and closing means for closing the seal carrier to the exterior whereby to seal off the drug in the chamber from the exterior, the capsule being retained in a housing and the seal carrier being removably attached to one of the housing and the capsule, and connecting means for connecting said article to a needleless injector power source wherein the closing means comprises a plug inserted in the seal carrier wherein the closing means comprises a plug inserted in the seal carrier.