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US 6,280,383 B1Granted
Magnetic resonance imaging
AssigneeFonar Corporation
InventorRaymond V Damadian
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AssigneeFonar Corporation
InventorRaymond V Damadian
Estimating the term…
The present invention is a method of studying tissue metabolism with ordinary oxygen. First, a magnetic resonance image of the tissue of interest is acquired. Oxygen, predominantly in the form of oxygen-16, is then delivered to the tissue. A magnetic resonance image of the tissue of interest is then acquired when the tissue is in the state of increased oxygenation. The first and second images are compared to determine the effect of the delivery of oxygen on the tissue based on changes in image characteristics, such as image contrast, image intensity and the morphology of tissues in the image. A relative measure of the degree of tissue oxygenation before and after the delivery of oxygen may be determined. The oxygen may be administered by inhalation of gaseous oxygen. The tissue may also be directly perfused by gaseous oxygen. The oxygen may be administered in combination with an oxygen carrier molecule, such as hemoglobin or heme. Preferably, only trace amounts of oxygen-17 is present. Oxygen substantially in its naturally occurring isotopic preparations is preferably delivered.
A method of studying tissue metabolism comprising:
A method of studying tissue metabolism comprising:
A method of studying tissue metabolism comprising:
A method of studying tissue metabolism comprising:
Dependencies are inferred from the claim text.