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US 6,278,039 B1Granted
C. elegans deletion mutants
AssigneeAxys Pharmaceuticals, Inc.
InventorsCarl Johnson, Bethany Westlund, Dianne Parry
Life of this patent
Estimating the term…
Abstract
Provided are worms having deletions in genes associated with Alzheimer's disease and methods for detecting genes and compounds involved in the causation of Alzheimer's disease or useful for the treatment of Alzheimer's disease. A novel method for constructing deletions in the nematode is also provided.
Claims1
A nematode having null mutations in hop-1 and sel-12, said nematode having a combined maternal-effect embryonic lethality and egg laying defective phenotype, at least one of said mutations being introduced by artifice, wherein said nematode is a C. elegans nematode.
Dependencies are inferred from the claim text.