Process for preparation of aromatic compounds
AssigneeVictrex Manufacturing Limited
InventorsJames Hanley Clark, David Adams
Life of this patent
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Abstract
There is disclosed a process for the preparation of a compound of general formula (I), wherein Y and Z each independently represent a fluorine atom or a hydroxy group, and a, b, c and d independently represent 0, 1, 2 or 3 provided that the sum of a, b, c, and d is 1, 2, 3 or 4; the process comprising treating a compound of general formula (II), wherein a, b, c, and d are as described above and L1 and L2 each independently represent an active group provided that either Y and L1 are different or Z and L2 are different, with a fluorinating system in the presence of oxygen. A preferred compound of general formula (I) is 4,4′-difluorobenzophenone which may be prepared from 4,4′-dinitrophenylmethane using tetramethylammonium fluoride.
Claims11
A process for the preparation of a compound of general formula
- wherein Y and Z each independently represent a fluorine atom or a hydroxy group, and a, b, c and d independently represent 0, 1, 2 or 3 provided that the sum of a, b, c and d is 1, 2, 3 or 4, the process comprising treating a compound of general formula
- wherein a, b, c and d are as described above and L1 and L2 each independently represent a leaving group or a group which is oxidisable to a leaving group provided that either Y and L1 are different or Z and L2 are different, with a fluorinating system in the presence of oxygen.
A process according to any preceding claim wherein said fluorinating system is involved in both the oxidation of the —CH2— groups and in the reaction of the group L1 and/or group L2.
Dependencies are inferred from the claim text.