Process for the preparation of acyl heteroaromatic compounds from heteroaromatic compounds by metal ion exchanged clays
AssigneeCouncil of Scientific and Industrial Research
InventorsBoyapati Manoranjan Choudary, Mutyala Sateesh, Mannepalli Lakshmi Kantam, Kondapuram Vijaya Raghaven
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Abstract
The present invention relates to a process for the preparation of the acyl heteroaromatic compounds useful as important intermediates for drugs, pharmaceuticals and flavouring agents, said process comprising reacting an heteroaromatic compound selected from furan, thiophene and pyrrole with a C2-C5 acid anhydride as an acylating agent employing metal ion exchanged clays as catalysts at temperatures in the range of 0-130° C. for a period of 1-24 h, and separating the acyl heteroaromatic compound by a conventional method to obtain a product of high purity.
Claims11
A process for the preparation of acyl heteroaromatic compound useful as, important intermediates for drugs, pharmaceuticals and flavoring agents, said process comprising reacting a heteroaromatic compound selected from furan, thiophene and pyrrole with a C2-C5 acid anhydride as an acylating agent employing metal ion exchanged clays as catalysts at temperatures in the range of 0-130° C. for a period of 1-24 h, and separating the acyl heteroaromatic compound by a conventional method to obtain a product of high purity.
Dependencies are inferred from the claim text.