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US 6,274,736 B1Granted
Chromatographic enantiomer separation of lactones
AssigneeBayer Aktiengesellschaft
InventorsWalter Lange, Rolf Grosser, Burkhard Köhler, Stefan Michel, Bruno Bömer, Uwe Zweering
Life of this patent
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Abstract
The present invention relates to the use of optically active polymers of N-acryloyl-phenylalanine neomenthylamide as such, in crosslinked form and/or in carrier-bonded form as stationary phases for the chromatographic separation of enantiomers of lactones.
Claims4
A process for the chromatographic separation of a mixture of enantiomers of a lactone
- into separate enantiomers thereof, said process comprising separating the separate enantiomers from a mobile phase comprising a mixture of the enantiomers by means of a chiral stationary phase comprising A) an optically active polymer selected from the group consisting of an optically active polymer of N-acryloyl-S-phenylalanine d-neomenthyl-amide and an optically active polymer of an enantiomer of N-acryloyl-S-phenylalanine d-neomenthyl-amide, B) a crosslinked form of said optically active polymer and/or C) a carrier-bonded form of said polymer.
Dependencies are inferred from the claim text.