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US 6,274,734 B1Granted
Process for making pyrimidine derivatives
AssigneeHoffman-La Roche Inc.
InventorWolfgang Göhring
Life of this patent
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Abstract
The present invention provides a process for the manufacture of pyrimidines of formula I: wherein R1, R2, R3 each independently represent hydrogen, C1-7-alkyl, or C1-7-alkoxy, A signifies —CN, a carbanionic R4-alkynyl residue, in which R4 is hydrogen or C1-7-alkyl, or a carbanionic residue of the malonic acid derivative of formula III in which B and B′ independently represent —CN, —COOR5, or —C(O)R5, wherein R5 is alkyl or aryl.
Claims6
A compound of the formula:
- wherein R1, R2, R3 each independently is hydrogen, C1-7-alkyl, or C1-7-alkoxy, and salts thereof.
A compound of the formula:
- wherein R1, R2, R3 each independently is hydrogen, C1-7-alkyl, or C1-7-alkoxy, and salts thereof.
Dependencies are inferred from the claim text.