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US 6,274,713 B1Granted
Polychelants
AssigneeSalutar, Inc.
InventorsPaul F. Sieving, Alan David Watson, Steven C. Quay, Scott Michael Rocklage
Life of this patent
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Abstract
Invention is directed to polychelants and their metal chelates which are useful in diagnostic imaging. The polychelants comprise a plurality of macrocyclic chelant moieties, eg. DOTA residues, conjugated by thiourea, urea or glycinamide linkages to a backbone moiety through a donor atom.
Claims21
A polychelant compound comprising a backbone moiety to which is covalently bonded at least 20 macrocyclic chelant moieties, wherein the backbone moiety contains one or more amino groups;
- each macrocyclic chelant moiety is capable of complexing metal ions;
- each macrocyclic chelant moiety contains a donor atom;
- and
- each macrocyclic chelant moiety is linked to said backbone moiety via a thiourea, an urea, or a glycinamide linkage bonded to the donor atom;
- or a metal chelate or a salt thereof.
2 more elements
Dependencies are inferred from the claim text.