Method for delaying the onset of alheimer's disease and for treatment or delaying the onset of other amyloidosis-related diseases/disorders
AssigneesSouth Alabama Medical Science Foundation, New York University
InventorsMiguel A. Pappolla, Blas Frangione, Jorge Ghiso
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Abstract
The present invention relates to a method of using melatonin to reduce, inhibit or reverse the formation of amyloid fibrils and amyloid or amyloid-like deposits. The present invention also relates to a method for delaying the onset of Alzheimer's Disease or other amyloidosis-related diseases/disorders or for treating such diseases/disorders by administering an effective amount of melatonin to a subject in need thereof.
Claims12
A method for delaying the onset of Alzheimer's Disease in individuals predisposed to Alzheimer's Disease or for treating or delaying the onset of other amyloidosis-related diseases/disorders, comprising administering an effective amount of melatonin to a subject in need thereof to inhibit the formation of fibrils associated with Alzheimer's Disease or to reduce, inhibit or reverse the formation of fibrils or amyloid or amyloid-like deposits associated with amyloidosis-related diseases/disorders other than Alzheimer's Disease.
Dependencies are inferred from the claim text.