Preparation for the treatment of metabolic syndrome containing human growth hormone in combination with a cortisol synthesis inhibitor
AssigneeCortendo AB
InventorPer Mårin
Life of this patent
Estimating the term…
Abstract
Human growth hormone is used in combination with a cortisol synthesis inhibitor, in particular ketoconazole, for prevention or treatment of conditions related to Metabolis Syndrome (Neuroendocrine Syndrome). Administration can be supplemented by a sex hormone selected from testosterone and natural or synthetic estrogen. Also disclosed are corresponding pharmaceutical compositions.
Claims18
A method of treating or preventing metabolic syndrome in a mammal, which method comprises administering a cortisol synthesis inhibitor and growth hormone to said mammal in an amount effective to treat or prevent the clinical manifestations of metabolic syndrome.
A method of decreasing visceral fat mass associated with metabolic syndrome in a mammal, which method comprises administering a cortisol synthesis inhibitor and growth hormone to said mammal in an amount effective to reduce said visceral fat mass.
A medical product comprising (a) a cortisol synthesis inhibitor, and (b) growth hormone, as a combined preparation for simultaneous, separate or sequential use in treating or preventing metabolic syndrome or for decreasing visceral fat mass associated with metabolic syndrome.
A kit for use in treating or preventing metabolic syndrome comprising:
- (a) a first container comprising a cortisol synthesis inhibitor;
- and
- (b) a second container comprising growth hormone.
Dependencies are inferred from the claim text.