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US 6,274,568 B1Granted
Compounds for altering cell surface sialic acids and methods of use therefor
OwnerRonald L. Schnaar, Yoshitak Ichikawa +2inventors
InventorsRonald L. Schnaar, Yoshitak Ichikawa, Brian E. Collins, Thomas J. Fralich
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Abstract
The present invention is based on the identification of compounds in the form of biosynthetic precursors which can be used to modulate neuronal growth, inhibit cellular entry by pathogens and modulate immune responses. The invention further describes acylated mannosamines, and derivatives thereof, which can be used to alter the sialic acid substituents of sialoglycoconjugates.
Claims19
A acylated N-mannosamine compound.
A pharmaceutical composition comprising an acylated mannosamine in a pharmaceutically aceptable carrier.
Dependencies are inferred from the claim text.