Cacnglike3 polynucleotides and expression systems
AssigneeSmithKline Beecham Corporation
InventorsDavid Malcolm Duckworth, Philip David Hayes
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Abstract
CACNGLIKE3 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing CACNGLIKE3 are calcium ion channel family members and CACNGLIKE3 polynucleotides encode for these calcium ion family proteins. Polynucleotides comprising the nucleotide sequences of the present invention provide means for production and manipulation of the CACNGLIKE3 polypeptides. The present invention also provides for the use of CACNGLIKE3 polynucleotides in recombinant expression systems.
Claims9
An isolated polynucleotide comprising a nucleotide sequence encoding the polypeptide of SEQ ID NO:2.
An isolated polynucleotide comprising the polynucleotide sequence set forth in SEQ ID NO:1.
An isolated polynucleotide which is fully complementary
- (a) a nucleotide sequence encoding the polypeptide of SEQ ID NO:2;
- (b) a nucleotide sequence comprising the polynucleotide sequence of SEQ ID NO:1;
- or
- (c) a nucleotide sequence consisting of the polynucleotide sequence of SEQ ID NO:1.
An expression vector comprising a polynucleotide, wherein said expression vector is capable of producing a polypeptide comprising the amino acid sequence of SEQ ID NO:2 when said expression vector is present in a compatible host cell.
A process for producing a recombinant host cell which comprises the step of introducing an expression vector comprising a polynucleotide capable of producing a polypeptide comprising the amino acid sequence of SEQ ID NO:2 into a cell such that the host cell, under appropriate culture conditions, produces said polypeptide.
Dependencies are inferred from the claim text.