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OwnerHarold Norris Weller, III, Waldemar Ruediger +1inventors
InventorsHarold Norris Weller, III, Waldemar Ruediger, R. Michael Lawrence
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The simultaneous synthesis of diverse organic compounds is performed in stackable modules which are moveable among nesting sites located on work station platforms. The reactor module includes a heat transfer block adapted to receive an array of reactor vessels, preferrably in the form of solid phase extraction cartridges without sorbent, each with an outlet port. A plurality of valves are located below the vessels. The valves consist of rows of gang-controlled stopcocks which regulate the passage of fluids from the reactor vessel outlet ports into aligned channels, each formed by a pair of threated Leur tip adapters. The reactor module may be situated over a discharge module. The inlet openings in the discharge module accept the threaded ends of the Leur tip adapters. The discharge module may consist of a multi-well collector block or a drain block. An introduction module, which includes a pressure plate having an array of openings and a septum, may be received over the reactor module. The downwardly projecting rim defining each pressure plate opening cooperates with the septum to engage the mouth of the aligned reactor vessel to maintain a fluid tight seal.
Apparatus for the simultaneous synthesis of multiple organic compounds, the apparatus comprising a reactor module adapted to receive an array of individual reactor vessels, a plurality of reactor vessels each having an outlet port and mechanical valve means for regulating the passage of fluids through said reactor vessel output ports, said valve means comprising an array of stopcocks, each of said stopcocks having an associated movable control arm and means for simultaneously rotating said control arms to open and close said stopcocks, said means for simultaneously rotating said control arms comprising first and second relatively moveable rails and means for connecting said control arms to each of said rails such that the relative movement of said rails simultaneously rotates said control arms connected thereto, each of said rails comprising a plurality of protrusions and recesses, said protrusions of one of said rails being received within said recesses of the other of said rails, when said rails are moved toward each other.
Apparatus for the simultaneous synthesis of multiple organic compounds, the apparatus comprising a reactor module adapted to receive an array of individual reactor vessels, a plurality of reactor vessels each having an outlet port, valve means for regulating the passage of fluids through said reactor vessel output ports, an introduction module and means for mounting said introduction module over said rector module, said introduction module comprising a gas manifold, a pressure plate and a septum.
Dependencies are inferred from the claim text.