Back to results
US 6,271,399 B1Granted
Endothelin receptor antagonists
AssigneeSmithKline Beecham Corporation
InventorsRussell Donovan Cousins, John Duncan Elliott, Maria Amparo Lago, Jack Dale Leber, Catherine Elizabeth Peishoff
Life of this patent
Estimating the term…
Abstract
Indane and indene compounds are described which are endothelin receptor antagonists.
Claims7
A compound selected from the group consisting of:
- Methyl-3-(3,4-Methylenedioxypbenyl)-6-(prop-1-yloxy)-1-oxo-indene-2-carboxylate;
- Methyl-( 1RS)- 1-hydroxy-(4-methoxy-2-methoxymethoxyphenyl)- 1-3-(3,4-methylenedioxyphenyl)-6-(prop-1-yloxy)indene-2-carboxylate;
- (+)Methyl-(1S,2S,3S)-3-(4-methoxy-2-methoxymethoxyphenyl)-1-(3,4-methylenedioxyphenyl)-5-(prop-1-yloxy)indane-2-carboxylate;
- (+)Methyl-(1S,2S,3S)-3-(2-Hydroxy-4-methoxyphenyl)-1-(3,4-methylenedioxyphenyl)-5-(prop-1-yloxy)indane-2-carboxylate;
- (+)Methyl-(1S,2S,3S)-3-(2-Carboethoxymethoxy-4-methoxyphenyl)-1-(3,4-methylenedioxyphenyl)-5-(prop-1-yloxy)indane-2-carboxylate;
- or
- Methyl (1SR, 2SR, 3SR)-3-[2-(2-hydroxyeth-1-yloxy)methoxyphenyl]-1-(3,4-methylenedioxy phenyl)-5-propoxyindane-2-carboxylate.
4 more elements
Dependencies are inferred from the claim text.