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US 6,271,354 B1Granted
Chimeric viral proteins
AssigneeThomas Jefferson University
InventorsAlagarsamy Srinivisan, Hilary Koprowski
Life of this patent
Estimating the term…
Abstract
Chimeric viral proteins and nucleic acid constructs that code for them and are useful as therapeutic agents.
Claims18
A chimeric viral protein comprising:
- 1) a protein of a virus;
- and
- 2) a polypeptide of said virus,
- said polypeptide joined by a peptide linkage to said viral protein in said chimeric protein, said polypeptide not normally joined by said peptide linkage to said protein in said virus or in cells infected by said virus.
1 more element
A chimeric viral protein comprising:
- 1) a non-capsid protein of a virus, the non-capsid protein not comprising a polypeptide proteolytic cleavage site for cleavage by a proteolytic enzyme;
- 2) a polypeptide of the virus, the polypeptide joined by a peptide linkage to the viral protein in said chimeric protein,
- wherein the polypeptide is not normally joined by the peptide linkage to the non-capsid protein in said virus or in cells infected by the virus.
Dependencies are inferred from the claim text.