Eosinophil eotaxin receptor
AssigneeMerck & Co., Inc.
InventorsBruce L. Daugherty, Julie A. Demartino, Salvatore J. Siciliano, Martin S. Springer
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Abstract
The eosinophil eotaxin receptor has been isolated, cloned and sequenced. This receptor is a human β-chemokine receptor and has been designated “CC CKR3”. The eosinophil eotaxin receptor may be used to screen and identify compounds that bind to the eosinophil eotaxin receptor. Such compounds would be useful in the treatment and prevention of atopic conditions including allergic rhinitis, dermatitis, conjunctivitis, and particularly bronchial asthma.
Claims4
A recombinant human eosinophil eotaxin receptor having the amino acid sequence as set forth in SEQ ID NO:1.
Dependencies are inferred from the claim text.