Method of treating cancer with a benzimidazole and a chemotherapeutic agent

A method of treating cancer susceptible to treatment in a warm blooded mammal comprising:

• administering to the mammal a safe and effective amount of a cyclophosphamide to reduce the cancer significantly;
• and
• administering to the mammal a pharmaceutical composition comprising an enhanced safe and effective amount of a benzimidazole of the formula:
• wherein:
• X is hydrogen, halogen, alkyl of less than 7 carbon atoms, or alkoxy of less than 7 carbon atoms;
• n is a positive integer of less than 4;
• Y is hydrogen, chloro, nitro, methyl, or ethyl;
• R is hydrogen, an alkyl group of from 1 to 8 carbon atoms, or CONHR3 wherein R3 is alkyl of less than 7 carbons;
• and
• R2 is 4-thiazolyl or NHCOOR1 wherein R1 is an aliphatic hydrocarbon of less than 7 carbon atoms.