Pasteurella neuraminidase coding sequences and diagnostic methods
AssigneeUniversity of Georgia Research Foundation, Inc.
InventorsMargie Lee, Susan Sanchez, Adam Henk
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Abstract
Provided are Pasteurella multocida coding sequences, recombinant DNA molecules, recombinant host cells and methods for making recombinant neuraminidase. Also provided by the present disclosure are immunogenic compositions containing recombinant P. multocida neuraminidase and antigenic peptides derived in sequence therefrom and antibodies specific for P. multocida neuraminidase as well as immunoassays specific for P. multocida neuraminidase, which immunoassays are useful in the detection or diagnosis of P. multocida infections and/or carrier states.
Claims13
A non-naturally occurring recombinant DNA molecule comprising a coding sequence having at least about 90% DNA sequence homology to SEQ ID NO:4, nucleotides 251 to 1486, and encoding a neuraminidase from a Pasteurella multocida and a second sequence which is not associated in nature with said coding sequence.
Oligonucleotides useful in the identification of a Pasteurella multocida, said oligonucleotides useful in nucleic acid hybridization or in polymerase chain reaction, and said oligonucleotides having sequences as given in SEQ ID NO:6 and SEQ ID NO:7.
Dependencies are inferred from the claim text.