Group O HIV-1, fragments of such viruses, and uses thereof
AssigneesInstitut National De La Sante Et De La Recherche Medicale (Inserm), Assistance Publique-Hopitaux de Paris
InventorsFrançois Simon, Sentob Saragosti, Ibtissam Loussert-Ajaka, Thoai-Duong Ly, Marie-Laure Chaix-Baudier
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Abstract
Group HIV-1 retrovirus strains, particularly the strains known as BCF02, BCF01, BCF06, BCF07, BCF08, BCF11, BCF03, BCF09, BCF12, BCF13 and BCF14, fragments of said retroviruses, and the uses thereof as a diagnostic reagent and as an immunogen, are disclosed.
Claims8
An isolated nucleic acid obtained from a group of O HIV-1, wherein the sequence of said nucleic acid is selected from the group consisting of:
- SEQ ID NO:1, SEQ ID NO:2, SEQ ID NO:3, SEQ ID NO:4, SEQ D NO:5, SEQ ID NO:6, SEQ ID NO:7, SEQ ID NO:50, SEQ ID NO:51, SEQ ID NO:52, SEQ ID NO:53, SEQ ID NO:8, SEQ ID NO:9, SEQ ID NO:10, SEQ ID NO:11, SEQ ID NO:12, SEQ ID NO:13, SEQ ID NO:
- 14, SEQ ID NO:54, SEQ ID NO:55, SEQ ID NO:56, SEQ ID NO:57, SEQ ID NO:15, SEQ ID NO:16, SEQ ID NO:17, SEQ ID NO:
- 18, SEQ ID NO:19, SEQ ID NO:20, SEQ ID NO:21, SEQ ID NO:58, SEQ ID NO:59, SEQ ID NO:60, and SEQ ID NO:61.
An in vitro diagnostic reagent for a group of O HIV-1, wherein said diagnostic reagent is selected from the group consisting of SEQ ID NOS:
- 22, 23, 24, and 25, which sequences may be used as primers for the amplification of a gp41 fragment from a group O HIV-1 viruses.
Dependencies are inferred from the claim text.