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US 6,270,790 B1Granted
Soft, convex shaped chewable tablets having reduced friability
AssigneeMxNeil-PPC, Inc.
InventorsRonni L. Robinson, James R. Damon, James R. Mossop, Michael D. Palmer
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Abstract
The present invention relates to a compressed, chewable tablet containing at least one active ingredient, a water-disintegratable, compressible carbohydrate and a binder. These components are dry blended and compressed into convex-shaped tablet having a hardness of about 2 to about 11 kp/cm2 and friability less than 1%.
Claims8
A compressed, chewable tablet having opposed major surfaces, comprising:
- about 0.1 to about 60% of at least one active ingredient coated with a taste masking coating;
- about 30 to about 90% of a water-disintegratable, compressible carbohydrate selected form the group consisting of mannitol, sorbitol, maltitol, dextrose, sucrose, xylitol, lactose, and mixtures thereof;
- about 1 to about 30% of a binder selected form the group consisting of cellulose, cellulosic derivatives, polyvinyl pyrrolidone, starch, modified starch and mixtures thereof;
- about 0.1 to about 5% of a lubricant;
- 0 to about 5% sweetener;
- 0 to about 5% flavor;
- 0 to about 5% color, by weight of said tablet;
- and
- said face surfaces having a convex shape and said tablet having a hardness of about 2 to about 11 kp/cm2 and a friability of less than about 1%.
6 more elements
Dependencies are inferred from the claim text.