Delivery of nucleic acid
AssigneeCambridge Drug Discovery Holdings, LTD
InventorsStephen James Russell, Frances Joanne Morling
Life of this patent
Estimating the term…
Abstract
Disclosed are various compositions for use in the delivery of nucleic acid to a target cell including: a composition comprising a calcium salt in particulate form, the nucleic acid to be delivered, and one or more further components to enhance the efficiency of delivery of the nucleic acid to a target cell, the nucleic acid and the one or more further components being complexed with the particulate calcium salt; and methods of delivering a nucleic acid to a target cell.
Claims16
A method of delivering a nucleic acid to a target cell, comprising mixing a calcium salt precipitate with said nucleic acid, wherein said nucleic acid is packaged within a eukaryotic viral particle, so as to form a complex;
- and
- contacting said complex to said target cell.
A method of delivering a nucleic acid to a target cell, comprising packaging said nucleic acid within a eukaryotic viral particle;
- mixing said nucleic acid containing eukaryotic viral particle with one or more components to enhance the efficiency of delivery of the nucleic acid to a target cell;
- adding a calcium salt precipitate to said nucleic acid containing eukaryotic viral particle and said one or more components so as to form a complex;
- and
- contacting said complex to said target cell.
Dependencies are inferred from the claim text.