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US 6,270,748 B1Granted
Contrast enhancing agent having a polymeric core and polymeric shell
AssigneeRohm and Haas Company
InventorsNikoi Annan, Charles Howard Reynolds, Steven Howard Shaber, Eric Jon Langenmayr
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Abstract
The present invention pertains to an image enhancing agent having a polymeric core including an image-enhancing compound chemically bound thereto and a polymeric shell surrounding the core and compound. The agent may be used for enhancing MRI images, by introducing gadolinium or other appropriate material into the core. Generally, the core is formed from an acid monomer and an esterified monomer. Preferably, a cross-linking monomer is included in the core.
Claims10
An image enhancing agent comprising:
- a polymeric core having an image-enhancing compound chemically bound thereto;
- and
- a polymeric shell surrounding said core and compound,
- wherein said core comprises a polymer formed from a monomer mixture comprising between 10 and 90% acid monomer, and 10 and 90% esterified monomer, and
- wherein said compound is a metal that binds to acidic regions in said core.
2 more elements
Dependencies are inferred from the claim text.