Nanostructured ceramics and composite materials for orthopaedic-dental implants
AssigneeRensselaer Polytechnic Institute
InventorsThomas J. Webster, Richard W. Siegel, Rena Bizios
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Abstract
Methods for enhancing osteoblast functions on a surface of an orthopaedic/dental implant and enhancing osseointegration of an orthopaedic/dental implant consist of providing an orthopaedic/dental implant comprising one or more nanostructured ceramic having a grain size of 1-100 nm or a composite of one or more adhesion-promoting polymers and one or more nanostructured ceramic having a grain size of 1-100 nm, and placing the implant in the body of an animal, where it may be exposed to osteoblast cells. Alumina, titania, or hydroxyapatite is preferred as the nanostructured ceramic.
Claims22
A method for enhancing osteoblast functions on a surface of an orthopaedic/dental implant comprising:
- providing an orthopaedic/dental implant comprising one or more nanostructured ceramic having a grain size of 1-100 nm or a nanocomposite of one or more nanostructured ceramic having a grain size of 1-100 nm and at least one of an adhesion-promoting peptide and a non-peptide polymer, and
- exposing said orthopaedic/dental implant to osteoblast cells.
A method for enhancing osseointegration of an orthopaedic/dental implant comprising:
- providing an orthopaedic/dental implant comprising one or more nanostructured ceramic having a grain size of 1-100 nm or a nanocomposite comprising one or more nanostructured ceramic having a grain size of 1-100 nm and at least one of an adhesion-promoting peptide and a non-peptide polymer, and
- placing said orthopaedic/dental implant in an animal.
An orthopaedic/dental implant consisting essentially of one or more nanostructured ceramics having a grain size of 1-100 nm and selected from the group consisting of alumina, titania and combinations thereof.
An orthopaedic/dental implant comprising a nanocomposite of one or more nanostructured ceramic having a grain size of 1-100 nm and at least one of an adhesion-promoting peptide and a non-peptide polymer.
An orthopaedic/dental implant comprising one or more nanostructured ceramics having a grain size of 1-100 nm, and wherein said one or more nanostructured ceramics is other than an apatite.
Dependencies are inferred from the claim text.