Back to results
US 6,269,649 B1Granted
High-pressure freezing system
AssigneeLeica Mikrosysteme GmbH
InventorDaniel Studer
Life of this patent
Estimating the term…
Abstract
The invention relates to a high-pressure freezing system in which the pressure build-up ensues from a prestressed pneumatic cylinder. This results in a particularly rapid pressure rise in the sample holder.
Claims24
A high-pressure freezing system to attain an amorphous state during the rapid freezing of aqueous substances, in particular biological samples, the system comprises:
- a cooling device
- a device for pressure build-up which has a drive cylinder with a pressure liquid and a high-pressure cylinder which is driven by the drive cylinder, said high-pressure cylinder impinges the sample with the pressure liquid during high-pressure operation;
- and
- a prestressing device which has mechanically operated locking device which triggers a rapid pressure build-up in the high-pressure cylinder.
1 more element
A high-pressure freezing system to attain an amorphous state during the rapid freezing of biological samples, the system comprises:
- a cooling device,
- a device for pressure build-up which has a pneumatic cylinder with a pressure liquid and a high-pressure cylinder which is driven by the pneumatic cylinder, said high-pressure cylinder impinges the sample with the pressure liquid during high-pressure operation and,
- a prestressing device which has a mechanically operated locking device which triggers a rapid pressure build-up in the high-pressure cylinder.
Dependencies are inferred from the claim text.