Variant EGIII-like cellulase compositions
AssigneeGenencor International, Inc.
InventorsColin Mitchinson, Dan J. Wendt
Life of this patent
Estimating the term…
Abstract
The present invention relates to novel variant EGIII or EGIII-like cellulases which have improved stability. The variant cellulases have performance sensitive residues replaced to a residue having improved stability.
Claims20
A variant EGIII or EGIII-like cellulase, wherein said variant comprises a substitution or deletion at a position corresponding to one or more of residues T2, S3, A8, F10, S18, A24, S25, F30, G31, V36, L38, A42, A46, D47, Q49, Q61, Q64, I65, Q69, A83, S86, S90, V109, T110, Y111, K123, D126, S133, Q134, G135, V139, T145, Q162, N164, T166, Y168, N174, R180, K183, N186, G189, V192, L193, S205, G206, N209, A211, T214 and/or 1217 in EGIII from Trichoderma reesei.
A detergent composition comprising a surfactant and cellulase wherein said cellulase comprises a variant EGIII-like cellulase comprising a substitution or deletion at a surfactant sensitive residue at a position corresponding to one or more of residues T2, S3, A8, F10, S18, A24, S25, F30, G31, V36, L38, A42, A46, D47, Q49, Q61, Q64, I65, Q69, A83, S86, S90, V109, T110, Y111, K123, D126, S133, Q134, G135, V139, T145, Q162, N164, T166, Y168, N174, R180, K183, N186, G189, V192, L193, S205, G206, N209, A211, T214 and/or I217 in EGIII from Trichoderma reesei.
Dependencies are inferred from the claim text.