US 6,268,120 B1 · Isoalloxazine derivatives to neutralize biological contaminants

Abstract

Methods are provided for neutralization of microorganisms in fluids or on surfaces. Preferably the fluids contain blood or blood products and comprise biologically active proteins. Preferred methods include the steps of adding an activation-effective amount of a microorganism neutralizer with an isoalloxazine backbone to a fluid and exposing the fluid to a triggering event. Preferred triggering events include light of a suitable wavelength and intensity to activate the microorganism neutralizer or a pH sufficient to activate the microorganism neutralizer. Other fluids, including juices, water and the like, may also be decontaminated by these methods as may surfaces of foods, animal carcasses, wounds, food preparation surfaces and bathing and washing vessel surfaces. Compounds with an isoalloxazine backbone are also provided.

Claims7

Dependent claims

A method for treating a fluid to neutralize microorganisms which may be present therein, said fluid containing one or more components selected from the group consisting of protein, blood, and blood constituents, said method comprising:

(a) adding to said fluid a neutralization-effective amount of a microorganism neutralizer of formula:
wherein X is a halogen selected from the group consisting of chlorine, bromine and iodine, Ra, Rb and Rc are, independently of each other, selected from the group consisting of hydrogen, optionally substituted hydrocarbyl, and halogen selected from the group consisting of chlorine, bromine and iodine, and n is an integer from 0 to 20;
(b) exposing the fluid of step (a) to a triggering event whereby said microorganisms are neutralized.

Dependencies are inferred from the claim text.

Isoalloxazine derivatives to neutralize biological contaminants

Life of this patent

Isoalloxazine derivatives to neutralize biological contaminants

Life of this patent

Abstract

Claims7