Loading patent…
AssigneesBando Chemical Industries, Ltd., Hisamitsu Pharmaceutical Co., Inc.
InventorsKimihiro Fujii, Kazuo Tanaka, Kazuya Ikawa, Yasuhiro Ikeura, Shinji Yamasoto
Estimating the term…
A transdermal patch which comprises: a substrate sheet comprises a composite film formed of a resin composition comprising 100 parts by weight of a polyvinyl chloride-polyurethane composite and 2-10 parts by weight of a styrene-ethylene-butylene-styrene copolymer, a first adhesive layer on the one side of the composite film, and a polyalkylene terephthalate film adhered to the one side of the composite film by means of the first adhesive layer, a primer layer which comprises a saturated polyester resin and is formed on the surface of the polyalkylene terephthalate film; and a second adhesive layer comprising a styrene-diene-styrene block copolymer containing a pharmaceutical agent layered on the primer layer. A method for the manufacture of the above-mentioned substrate sheet comprises preparing the above resin composition molding the resin composition into a composite film by a calendar process, and then adhering a polyalkylene terephthalate film on one side of the composite film by means of an adhesive layer thereby forming the substrate sheet, and forming a primer layer comprising a saturated polyester resin on the outer surface of the polyalkylene terephthalate film.
A transdermal patch which comprises a substrate sheet which comprises a composite film formed of a resin composition consisting essentially of a mixture of 100 parts by weight of a polyvinyl chloride-polyurethane composite and 2-10 parts by weight of a styrene-ethylene-butylene-styrene copolymer, a polyurethane adhesive layer on one side of the composite film, and a polyalkylene terephthalate film adhered to said one side of the composite film by the first polyurethane adhesive layer;
A substrate sheet for use in a transdermal patch which comprises a composite film formed of a resin composition consisting essentially of a mixture of 100 parts by weight of a polyvinyl chloride-polyurethane composite and 2-10 parts by weight of a styrene-ethylene-butylene-styrene copolymer, a polyurethane adhesive layer on one side of the composite film, and a polyalkylene terephthalate film adhered to the composite film by means of the polyurethane adhesive layer.
A method for the manufacture of a substrate sheet for use in a transdermal patch which comprises preparing a resin composition consisting essentially of a mixture of 100 parts by weight of a polyvinyl chloride-polyurethane composite and 2-10 parts by weight of a styrene-ethylene-butylene-styrene copolymer, molding the resin composition into a composite film by a calendar process, and then adhering a polyalkylene terephthalate film on one side of the composite film by means of a polyurethane adhesive layer thereby forming the substrate sheet, and forming a primer layer comprising a saturated polyester resin on an outer surface of the polyalkylene terephthalate film.
Dependencies are inferred from the claim text.