US 6,267,782 B1Granted

Medical article with adhered antimicrobial metal

AssigneeSt. Jude Medical, Inc.

InventorsMatthew F. Ogle, William R. Holmberg, Richard F. Schroeder, Donald S. Guzik, M. William Mirsch, II, Darrin J. Bergman, Hallie A. Finucane, Katherine S. Tweden

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Abstract

A variety of new ways can be used for associating antimicrobial elemental metal with a medical article. The associated antimicrobial metal reduces the risk of infection associated with the medical use of the medical article. New medical articles are produced by some of these new approaches. Some of the methods involve ways of adjusting the dissociation rate of associated elemental metal such that desired degrees of antimicrobial activity can be achieved over selected periods of time.

Claims12

Dependent claims

A method for preparing a medical article comprising biocompatible material selected from the group consisting of tissue and biological polymer, said method comprising:

combining a metal composition and said biocompatible material in a solution under reducing conditions provided by the addition of a chemical reducing agent in the solution or by applying a current to the solution with said biocompatible material acting as a cathode, where said reducing conditions induce a reaction in which said metal composition is reduced that results in the deposition of antimicrobial metal in association with said biocompatible material.

Dependencies are inferred from the claim text.

Facts

Application: 09/143,989Filed 31 Aug 1998 · continuation in part
Priority: 20 Nov 1997
Granted: 31 Jul 2001
Term ends: Not estimatedThe source records don’t support an estimate.

Classification25 codes

A61L 31/16
Materials characterised by their function or physical properties , e.g. injectable or lubricating compositions, shape-memory materials, surface…:…
A01N 59/16
Biocides, pest repellants or attractants, or plant growth regulators containing elements or inorganic compounds: heavy metals; Compounds thereof
A61L 15/18
Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons: containing inorganic materials
A61L 15/44
Use of materials characterised by their function or physical properties: medicaments