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US 6,264,913 B1Granted
Non-invasive test for assessing bacterial overgrowth of the small intestine
AssigneeMetabolic Solutions, Inc.
InventorDavid A. Wagner
Life of this patent
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Abstract
Provided herein is a novel breath test for assessing bacterial overgrowth. The test involves administration of a labeled sorbitol or sorbitol derivative to a subject and measurement of the label in breath and/or blood.
Claims14
A method of assessing bacterial overgrowth in the small intestine of a subject comprising the steps of:
- a. administering an amount of carbon-labeled sorbitol or sorbitol derivative to said subject, wherein said sorbitol derivative has the characteristics of not being readily absorbed by said subject and being metabolizable by bacteria;
- b. collecting a specimnen from said subject;
- c. measuring an amount of labeled carbon in said specimen to obtain a measured amount;
- and
- d. comparing said measured amount with a positive standard and a negative standard to assess bacterial overgrowth in said subject,
- wherein said negative standard is an amount of expired labeled carbon in a control group without bacterial overgrowth, and wherein said positive standard is an amount of expired labeled carbon in a control group with bacterial overgrowth.
3 more elements
Dependencies are inferred from the claim text.