Production of polyketides in plants
AssigneeKosan Biosciences, Inc.
InventorsMary C. Betlach, James T. Kealey, Neal Gutterson, Ed Ralston
Life of this patent
Estimating the term…
Abstract
The present invention provides genetically altered plants and plant cells that have been modified to contain expression system(s) capable of expressing a functional polyketide synthase (PKS). The present invention further provides methods of producing PKS and polyketides using these plants and cells.
Claims65
Plant cells, plant parts or plants modified to contain at least one expression system effective to produce an aromatic polyketide synthase (PKS), wherein said aromatic PKS comprises a ketosynthase/acyl transferase (KS/AT) catalytic region, a chain-length factor (CLF) catalytic region and an acyl carrier protein (ACP) activity and produces an aromatic polyketide in said plant cells, plant parts or plants.
Plant cells, plant parts or plants modified to contain at least one expression system effective to produce a fungal polyketide synthase (PKS), wherein said fungal PKS comprises a ketosynthase/acyl transferase (KS/AT) catalytic region and an acyl carrier protein (ACP) activity and produces a fungal polyketide in said plant cells, plant parts or plants.
Dependencies are inferred from the claim text.