Flow-through peritoneal dialysis systems and methods with on-line dialysis solution regeneration

A system for conducting peritoneal dialysis comprising

• a pumping assembly to circulate peritoneal dialysis solution through a peritoneal cavity to perform peritoneal dialysis including a inlet branch to convey peritoneal dialysis solution into the peritoneal cavity and an outlet branch to withdraw peritoneal dialysis solution from the peritoneal cavity, and
• a regeneration assembly coupled in-line between the inlet and outlet branches, the regeneration assembly including a source of a regeneration solution that carries at least one agent for regenerating spent peritoneal dialysis solution, and a porous membrane having a first side, along which peritoneal dialysis solution is circulated by the pumping assembly from the outlet branch to the inlet branch, and a second side, along which the regeneration solution is circulated, the porous membrane being configured to transport waste from spent peritoneal dialysis solution into the regeneration solution and to transport the regenerating agent from the regeneration solution into spent peritoneal dialysis solution, the regeneration assembly operating to create from peritoneal dialysis solution in the outlet branch, a regenerated dialysis solution for conveyance through the inlet branch into the peritoneal cavity.