Systems and methods for local delivery of an agent
AssigneeC.R. Bard, Inc.
InventorsJohn E. Ahern, James F. Crittenden
Life of this patent
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Abstract
A system and method for implanting pellets into myocardial tissue for treatment of coronary artery restenosis, ischemic heart disease, or cardiac conduction of disturbances. The mechanism of delivery can be transcatheter via chambers of the heart, endoscopic pericardial approach via minimally invasive transthoracic access, or intraoperative pericardial approach during open-chest surgery. Noncardiac tissues can also be treated.
Claims16
A method for providing local delivery of a therapeutic agent comprising the steps of
- delivering and implanting sequentially a plurality of pellets containing a therapeutically effective amount of said therapeutic agent into the myocardial tissue.
A method for delivering a pellet containing a therapeutic agent, comprising the steps of
- providing a plurality of pellets each containing a therapeutically effective amount of a therapeutic agent,
- providing a catheter having a distal end adapted for delivering said pellets,
- guiding said catheter through a body lumen and disposing said distal end proximate a tissue wall, and
- delivering sequentially the pellets through said distal end with sufficient force to implant said pellet within said tissue wall.
A method for delivering a therapeutic agent to a septal artery, comprising the steps of
- providing a catheter having a distal end adapted for delivering a therapeutically effective amount of a therapeutic agent,
- guiding said catheter into the interior of a patient's heart, and
- disposing said distal end against a septal wall of the heart for sequentially implanting a plurality of pellets containing said therapeutic agent into the septal wall.
A method for treating vascular restenosis, comprising the steps of
- identifying a portion of tissue proximate to a site of a patient's vasculature to be treated for restenosis, and
- implanting sequentially a plurality of pellets containing a therapeutically effective amount of a therapeutic agent into the portion of a tissue.
Dependencies are inferred from the claim text.