US 6,248,559 B1Granted

Gene encoding human tau-protein kinase I and use thereof

AssigneeMitsubishi Chemical Corporation

InventorsAkihiko Takashima, Toshimitsu Hoshino, Kazutomo Imahori, Ken-ichi Saito, Akiko Shiratsuchi, Showbu Sato

Life of this patent

Estimating the term…

Abstract

A preventive or therapeutic agent for Alzheimer's disease which comprises a substance exhibiting an inhibitory action to tau-protein kinase I as an effective component is provided. A pharmaceutical composition comprising said agent and a method of inhibiting neuronal cell death in the brain are also provided.

Claims7

Dependent claims

An isolated polynucleotide encoding a human tau-protein kinase I comprising the amino acid sequence as set forth in SEQ ID No:

Dependencies are inferred from the claim text.

Facts

Application: 09/216,958Filed 21 Dec 1998 · division
Priority: JP 5-0411602 Mar 1993
Granted: 19 Jun 2001
Term ends: Not estimatedThe source records don’t support an estimate.

Classification9 codes

A61K 31/00
Medicinal preparations containing organic active ingredients
A61K 31/70
Medicinal preparations containing organic active ingredients: carbohydrates; Sugars; Derivatives thereof
C12N 9/12
Transferases: transferring phosphorus containing groups, e.g. kinases
C12N 15/1137
Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming…: against enzymes

Family

Application08/204,091Parent of this continuation-in-part · filed 2 Mar 1994
Application08/461,018Parent of this division · filed 5 Jun 1995
US 6,071,694 AParent of this division
Application08/461,018Parent of this continuation-in-part
US 6,248,559 B1This patent

From the US filing history. Foreign family members aren’t listed.

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