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US 6,245,933 B1Granted
Transesterification method for making cyanoacrylates
AssigneeClosure Medical Corporation
InventorsBernard Malofsky, Ibraheem T. Badejo
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Abstract
An α-cyanoacrylate may be formed by first condensing a cyanoacetate with paraformaldehyde or formaldehyde; reacting the polymer formed with an alcohol to transesterify the polymer; and depolymerizing the polymer to form α-cyanoacrylate monomers.
Claims20
A method for making α-cyanoacrylates, comprising:
- reacting a cyanoacetate with paraformaldehyde or formaldehyde to form a cyanoacrylate oligomer or polymer;
- reacting the cyanoacrylate oligomer or polymer with an alcohol to transesterify the cyanoacrylate oligomer or polymer;
- and
- depolymerizing the transesterified cyanoacrylate oligomer or polymer to form α-cyanoacrylates.
1 more element
Dependencies are inferred from the claim text.