Methods for the pulmonary delivery of biological agents
AssigneeAlliance Pharmaceutical Corp.
InventorsK. Michael Sekins, Thomas H. Shaffer, Marla R. Wolfson
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Abstract
Methods of delivering a therapeutic or diagnostic agent in a perfluorochemical liquid carrier are provided. In preferred embodiments, the disclosed methods use compositions in the form of an emulsion or a dispersion for delivery of a biological agent to the pulmonary air passages.
Claims50
A method for the delivery of a therapeutic or diagnostic biological agent to pulmonary air passages of a patient in need thereof comprising the steps of:
- combining said therapeutic or diagnostic biological agent in the form of a solid or immiscible liquid with a perfluorochemical liquid carrier to provide a pharmaceutical preparation;
- and
- administering said pharmaceutical preparation to the pulmonary air passages of said patient.
A method for the delivery of a therapeutic or diagnostic biological agent to pulmonary air passages of a patient in need thereof comprising the steps of:
- combining a liquid perfluorochemical with an immiscible liquid to form an emulsion wherein said emulsion further comprises at least one therapeutic or diagnostic biological agent;
- and
- administering the emulsion to the pulmonary air passages of said patient.
A method for the delivery of a therapeutic or diagnostic biological agent to pulmonary air passages of a patient in need thereof comprising the steps of:
- combining a liquid perfluorochemical with at least one therapeutic or diagnostic biological agent in solid form to provide a dispersion;
- and
- administering the dispersion to the pulmonary air passages of said patient.
Dependencies are inferred from the claim text.