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AssigneeRush-Presbyterian-St. Luke's Medical Center
InventorsLourens Jan Dirk Zaneveld, Robert Anthony Anderson, Jr., Xiao Hui Diao, Paul Robert Young, Jr., Donald Paul Waller, Sanjay Garg, Calvin J. Chany, II
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A method for the reduction in the risk of transmitting a sexually transmitted disease—especially HIV and/or HSV—during sexual activity is provided. This method generally comprises the application of an effective amount of an inhibitory agent, preferably as a topical formulation, to the area or areas of sexual contact prior to engaging in sexual activity. Inhibitory agents which are useful in the present invention include, for example, phosphorylated hesperidins, sulfonated hesperidins, polystyrene sulfonates, substituted benzenesulfonic acid formaldehyde co-polymers, H2SO4-modified mandelic acids, and the like. This method can be used by heterosexuals, homosexuals, and/or bisexuals engaged in a wide variety of sexual activities. In addition to anti-STD activity, these agents may also act as vaginal contraceptives; moreover, they generally have fewer side effects than conventional vaginal contraceptives (e.g., nonoxynol-9). For example, the compounds useful in this invention are generally not toxic to natural and beneficial vaginal flora and, thus, do not upset the local microbiological balance. The anti-STD method of the present invention has the added advantage that it can be implemented and controlled by either sexual party. Methods are also provided for reducing the risk of transmission of STD-causing organisms to health care providers and laboratory personnel (or other persons) who may come into contact with biological samples and specimens.
A method for reducing the risk of transmission and infection by a sexually transmitted disease through sexual activity between two or more parties where the parties are not at risk of pregnancy, said method comprising applying an effective amount of a polystyrene sulfonate to an area of the body to be engaged in the sexual activity of at least one of the parties prior to the sexual activity and then engaging in the sexual activity, wherein the polystyrene sulfonate contains less than about 50 ppm dichloroethane and wherein the sexually transmitted disease is caused by gonococci, papilloma virus, or chlamydia.
A method for reducing the risk of transmission and infection by a sexually transmitted disease through sexual activity between two or more parties where the parties are not at risk of pregnancy, said method comprising administering an effective amount of a polystyrene sulfonate to the area or areas of body of one or more of the parties in sexual contact during the sexual activity before or after the sexual activity, wherein the polystyrene sulfonate contains less than about 50 ppm dichloroethane and wherein the sexually transmitted disease is caused by gonococci, papilloma virus, or chlamydia.
A method for reducing the risk of transmission and infection by a sexually transmitted disease through sexual activity between two or more parties where none of the parties are at risk of pregnancy, said method comprising applying an effective amount of a polystyrene sulfonate to an area or areas of the body to be engaged in the sexual activity of at least one of the parties prior to the sexual activity, then engaging in the sexual activity, and then applying an additional amount of the polystyrene sulfonate to the area or areas which was engaged in the sexual activity, wherein polystyrene sulfonate contains less than about 50 ppm dichloroethane and wherein the sexually transmitted disease is caused by gonococci, papilloma virus, or chlamydia.
A method for reducing the risk of transmission and infection by a sexually transmitted disease through sexual activity between two parties wherein the first party is a male and the second party is a male or female and the sexual activity involves the penis of the first party and wherein the parties are not at risk of pregnancy, said method comprising applying a condom to the penis of the first party, applying an effective amount of a polystyrene sulfonate to an area of the body of the second party which is to be engaged in the sexual activity or to the condom of the first party prior to the sexual activity, and then engaging in the sexual activity, wherein the polystyrene sulfonate contains less than about 50 ppm dichloroethane and wherein the sexually transmitted disease is caused by gonococci, papilloma virus, or chlamydia.
A method for reducing the risk of transmission of a sexually transmitted disease to an uninfected individual through non-sexual contact with the bodily fluids of a potentially sexually transmitted disease infected person, said method comprising applying to the body or portion of the body of the uninfected individual an effective amount of a polystyrene sulfonate a time prior to likely contact with the bodily fluids or at a time as soon as possible after actual contact with the bodily fluids, wherein the polystyrene sulfonate contains less than about 50 ppm dichloroethane.
A method for reducing the risk of transmission and infection by a sexually transmitted disease through sexual activity between two or more parties, said method comprising applying an effective amount of a polystyrene sulfonate to an area of the body to be engaged in the sexual activity of at least one of the parties prior to the sexual activity and then engaging in the sexual activity, wherein the polystyrene sulfonate contains less than about 50 ppm dichloroethane, wherein the sexually transmitted disease is caused by gonococci, papilloma virus, or chlamydia, and wherein the parties to the sexual activity are selected from the group consisting of (1) groupings including only men, (2) groupings including only women, (3) heterosexual groupings wherein all females are diagnosed as being sterile or being post-menopausal or have been rendered sterile by a medical procedure, (4) heterosexual groupings wherein all males are diagnosed as being sterile or have been rendered sterile by a medical procedure, (5) heterosexual groupings wherein medically prescribed birth control methods are employed, and (6) heterosexual groupings wherein the sexual activity is anal sex.
A method for reducing the risk of transmission and infection by a sexually transmitted disease through sexual activity between two or more parties, said method comprising administering an effective amount of a polystyrene sulfonate to the area or areas of body of one or more of the parties in sexual contact during the sexual activity before or after the sexual activity, wherein the polystyrene sulfonate contains less than about 50 ppm dichloroethane, wherein the sexually transmitted disease is caused by gonococci, papilloma virus, or chlamydia, and wherein the parties to the sexual activity are selected from the group consisting of (1) groupings including only men, (2) groupings including only women, (3) heterosexual groupings wherein all females are diagnosed as being sterile or being post-menopausal or have been rendered sterile by a medical procedure, (4) heterosexual groupings wherein all males are diagnosed as being sterile or have been rendered sterile by a medical procedure, (5) heterosexual groupings wherein medically prescribed birth control methods are employed, and (6) heterosexual groupings wherein the sexual activity is anal sex.
A method for reducing the risk of transmission and infection by a sexually transmitted disease through sexual activity between two or more parties, said method comprising applying an effective amount of a polystyrene sulfonate to an area or areas of the body to be engaged in the sexual activity of at least one of the parties prior to the sexual activity, then engaging in the sexual activity, and then applying an additional amount of the polystyrene sulfonate to the area or areas which was engaged in the sexual activity, wherein polystyrene sulfonate contains less than about 50 ppm dichloroethane, and wherein the sexually transmitted disease is caused by gonococci, papilloma virus, or chlamydia, and wherein the parties to the sexual activity are selected from the group consisting of (1) groupings including only men, (2) groupings including only women, (3) heterosexual groupings wherein all females are diagnosed as being sterile or being post-menopausal or have been rendered sterile by a medical procedure, (4) heterosexual groupings wherein all males are diagnosed as being sterile or have been rendered sterile by a medical procedure, (5) heterosexual groupings wherein medically prescribed birth control methods are employed, and (6) heterosexual groupings wherein the sexual activity is anal sex.
A method for reducing the risk of transmission and infection by a sexually transmitted disease through sexual activity between two parties wherein the first party is a male and the second party is a male or female and the sexual activity involves the penis of the first party and wherein the parties are not at risk of pregnancy, said method comprising applying a condom to the penis of the first party, applying an effective amount of a polystyrene sulfonate to an area of the body of the second party which is to be engaged in the sexual activity or to the condom of the first party prior to the sexual activity, and then engaging in the sexual activity, wherein the polystyrene sulfonate contains less than about 50 ppm dichloroethane, and wherein the sexually transmitted disease is caused by gonococci, papilloma virus, or chlamydia, and wherein the parties to the sexual activity are selected from the group consisting of (1) groupings including only men, (2) groupings including only women, (3) heterosexual groupings wherein all females are diagnosed as being sterile or being post-menopausal or have been rendered sterile by a medical procedure, (4) heterosexual groupings wherein all males are diagnosed as being sterile or have been rendered sterile by a medical procedure, (5) heterosexual groupings wherein medically prescribed birth control methods are employed, and (6) heterosexual groupings wherein the sexual activity is anal sex.
Dependencies are inferred from the claim text.