α-amides of L-amino acid as fragrance precursors
AssigneeThe Gillette Company
InventorsCharles W. Slife, Judith Wolfe Laney, Virginia Streusand Goldman
Life of this patent
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Abstract
Disclosed are α-amides of L-amino acids that produce fragrance or attenuate or mask malodor. In particular, threonine amides, glycine amides, serine amides, and alanine amides can be used in the invention. Such α-amides of L-amino acids are useful for generating pleasant fragrances or attenuating or masking malodor upon cleavage of the α-amides of L-amino acids by bacteria in axillae. The α-amides of L-amino acids can be incorporated into skin treatment compositions and personal care products, such as deodorants, body sprays and antiperspirants, and used in methods for producing fragrance or attenuating or masking malodor.
Claims24
A composition for application to human skin comprising a dermatologically acceptable vehicle and an α-amide of an L-amino acid having the structure:
- wherein:
- the α-amide of the L-amino acid is present in an amount sufficient to produce fragrance or attenuate or mask malodor;
- R1 is H, CH3, CH2OH, or CH2(OH)CH3;
- and
- R2 is selected so that cleavage of the α-amide of the L-amino acid leaves an R2—CO2H having a neutral or pleasant odor.
Dependencies are inferred from the claim text.