Nucleic acid detecting reagent
OwnerUlf Landegren, Marek Kwiatkowskiinventors
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Abstract
The present invention provides a nucleic acid detecting agent able to interact with a target sequence through catenation. The invention provides a nucleic acid detecting reagent comprising a) two free nucleic acid ends which are at least partially complementary to and capable of hybridizing to two adjacent regions of a target nucleic acid sequence; and b) an intermediate segment between the ends, the intermediate segment being labeled with a least one detectable element selected from the group consisting of chromophores, fluorophores, luminescers, radiolabels, affinity groups and enzymes, wherein only the ends of the reagent hybridize to the target nucleic acid sequence.
Claims12
A nucleic acid detecting reagent comprising
- a) two free nucleic acid ends which are at least partially complementary to and capable of hybridizing to two adjacent regions of a target nucleic acid sequence;
- and
- b) an intermediate segment between said ends, said intermediate segment being labelled with a least one detectable element selected from the group consisting of chromophores, fluorophores, luminescers, radiolabels, affinity groups and enzymes,
- wherein only said ends of said reagent hybridize to said target nucleic acid sequence.
Dependencies are inferred from the claim text.