Certain diterpenes and extracts or concentrates of curcuma amada containing them for use as medicaments

A method for the treatment or amelioration of a hypersensitivity disease in an individual, which comprises administering to said individual an effective amount of a member selected from the group consisting of:

• (a) at least one compound of formula I
• wherein R1 and R2 are independently CH2OH or CHO (b) an extract or concentrate of Curcuma amada which comprises at least one compound of formula I;
• and (c) an extract or concentrate of Curcuma amada which comprises at least one compound of formula I and at least one compound selected from the group consisting of ocimene, dihydro-ocimene, α-pinene, α-curcumene, β-curcumene, linalool, cuminyl alcohol, keto-alcohol, turmerone, linalyl acetate, safrole, car-3-ene, myrcene, 1,8-cineol, limonene and perillene to treat or ameliorate said hypersensitivity disease.

A method for the treatment or amelioration of an autoimmune disease or an inflammatory disease in an individual, which comprises administering to said individual an effective amount of a member selected from the group consisting of:

• (a) at least one compound of formula I
• wherein R1 and R2 are independently CH2OH or CHO (b) an extract or concentrate of Curcuma amada which comprises at least one compound of formula I;
• and (c) an extract or concentrate of Curcuma amada which comprises at least one compound of formula I and at least one compound selected from the group consisting of ocimene, dihydro-ocimene, α-pinene, α-curcumene, β-curcumene, linalool, cuminyl alcohol, keto-alcohol, turmerone, linalyl acetate, safrole, car-3-ene, myrcene, 1,8-cineol, limonene and perillene to treat or ameliorate said autoimmune or inflammatory disease.

A method for the treatment or amelioration of an IgE mediated allergic reaction or condition in an individual, which comprises administering to said individual an effective amount of a member selected from the group consisting of:

• (a) at least one compound of formula I
• wherein R1 and R2 are independently CH2OH or CHO (b) an extract or concentrate of Curcuma amada which comprises at least one compound of formula I;
• and (c) an extract or concentrate of Curcuma amada which comprises at least one compound of formula I and at least one compound selected from the group consisting of ocimene, dihydro-ocimene, α-pinene, α-curcumene, β-curcumene, linalool, cuminyl alcohol, keto-alcohol, turmerone, linalyl acetate, safrole, car-3-ene, myrcene, 1,8-cineol, limonene and perillene to treat or ameliorate said IgE mediated allergic reaction or condition.