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US 6,231,590 B1Granted
Bioactive coating for vaso-occlusive devices
AssigneeSciMed Life Systems, Inc.
InventorsPaul C. Slaikeu, Joseph C. Eder, James J. Barry, Michael P. Wallace, Robert M. Abrams
Life of this patent
Estimating the term…
Abstract
This is a medical device for forming an embolism within the vasculature of a patient. More particularly, it is a vaso-occlusion device at least partially coated with a bioactive agent, a collagenous material, or a collagenous coating optionally containing or coated with other bioactive agents. A highly flexible vaso-occlusive device coated with such materials also forms a variation of the invention.
Claims48
A vaso-occlusive device comprising:
- a) a vaso-occlusive member;
- b) an inner coating on at least a portion of said vaso-occlusive member, said inner coating being free from protein;
- and
- c) a protein-based outer coating on said inner coating wherein said inner coating is not applied by plasma treatment.
1 more element
A vaso-occlusive device comprising:
- a) a vaso-occlusive member, and
- b) an inner material on at least a portion of said vaso-occlusive member, said inner material being free from protein;
- and
- c) a protein-based outer coating on said inner material wherein said inner material is not applied by plasma treatment.
1 more element
A vaso-occlusive device comprising:
- a) a vaso-occlusive member having a flexibility;
- and
- b) an inner material on at least a portion of said vaso-occlusive member, said inner material being free from protein;
- and
- c) a protein-based outer coating on said inner material in such amount and thickness that the flexibility of the vaso-occlusive device is not more than 35% stiffer than said vaso-occlusive member wherein said inner material is not applied by plasma treatment.
2 more elements
A vaso-occlusive device comprising:
- a) a vaso-occlusive member;
- b) an inner coating on at least a portion of said vaso-occlusive member, said inner coating being free from protein;
- and
- c) a bioactive-material-based outer coating on said inner coating wherein said inner coating is not applied by plasma treatment.
1 more element
Dependencies are inferred from the claim text.