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US 6,228,845 B1Granted
Therapeutic intraluminal stents
AssigneeMedtronic, Inc.
InventorsMaura G. Donovan, Paul M. Stein
Life of this patent
Estimating the term…
Abstract
This invention relates to an intraluminal stent having a lumen-wall contacting surface and a lumen-exposed surface wherein the stent comprises a first polymer composition comprising fibrin and wherein the stent is suitable to deliver virus to the wall of a lumen of the body. The invention also relates to methods for making the stent and to methods for delivering nucleic acid to cells accessible from a wall of a body lumen.
Claims20
A method for making a stent to deliver nucleic acid to cells accessible from a wall of a body lumen comprising the steps of:
- providing a stent comprising a lumen-wall contacting surface, a lumen-exposed surface, and a first polymer composition comprising fibrin covering at least a portion of the lumen-wall contacting surface to form a polymer covered stent;
- preparing virus capable of delivering nucleic acid to the walls of a body lumen;
- and
- loading the virus on the first polymer composition.
1 more element
A virus delivery composition comprising:
- a polymer composition comprising fibrin;
- and
- virus capable of delivering nucleic acid to a cell.
Dependencies are inferred from the claim text.