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US 6,221,026 B1Granted
Breath test for the detection of various diseases
OwnerMichael Phillipsinventor
Life of this patent
Estimating the term…
Abstract
The alkane profile, comprising the alveolar gradients of n-alkanes in breath having 4 to 20 carbons, is determined for the diagnosis of disease in mammals, including humans.
Claims10
A process for determining the presence or absence of disease in a mammal, including a human, which comprises;
- collecting a representative sample of alveolar breath from the mammal;
- collecting a representative sample of ambient air;
- analyzing the samples of breath and air to determine content of n-alkanes having 2 to 20 carbon atoms, inclusive;
- calculating alveolar gradients of the n-alkanes having 2 to 20 carbon atoms, inclusive, in the breath sample in order to determine an alkane profile;
- and
- comparing the alkane profile to baseline alkane profiles calculated for mammals known to be free of the disease to be determined with a finding of differences in the alkane profile from the baseline alkane profile being indicative of the presence of the disease.
3 more elements
A process for determining the presence of breast cancer in a human, which comprises;
- collecting a representative sample of alveolar breath from a human;
- collecting a representative sample of ambient air;
- analyzing the collected samples of breath and of air to determine content of n-alkanes having 2 to 20 carbon atoms, inclusive;
- calculating alveolar gradients of the n-alkanes having 2 to 20 carbon atoms, inclusive, in the breath sample in order to determine an alkane profile;
- calculating a baseline alkane profile for humans known to be free of breast cancer;
- and
- comparing the alkane profile to the baseline alkane profile with a finding of downward displacement in the alkane profile from the baseline alkane profile being indicative of the presence of breast cancer.
4 more elements
A process for determining the presence of ischemic heart disease in a human, which comprises;
- collecting a representative sample of alveolar breath from a human;
- collecting a representative sample of ambient air;
- analyzing the collected samples of breath and of air to determine content of n-alkanes having 2 to 20 carbon atoms, inclusive;
- calculating alveolar gradients of the n-alkanes having 2 to 20 carbon atoms, inclusive, in the breath sample, in order to determine an alkane profile;
- calculating a baseline alkane profile for humans known to be free of ischemic heart disease;
- comparing the alkane profile to the baseline alkane profile with a finding of upward displacement in the alkane profile from the baseline alkane profile being indicative of the presence of ischemic heart disease.
3 more elements
A process for determining the presence of renal disease in a human, which comprises;
- collecting a representative sample of alveolar breath from a human;
- collecting a representative sample of ambient air;
- analyzing the collected samples of breath and of air to determine content of n-alkanes having 2 to 20 carbon atoms, inclusive;
- calculating alveolar gradients of the n-alkanes having 2 to 20 carbon atoms, inclusive, in the breath sample in order to determine an alkane profile;
- calculating a baseline alkane profile for humans known to be free of renal disease;
- and
- comparing the alkane profile to the baseline alkane profile with a finding of downward displacement in the alkane profile from the baseline alkane profile being indicative of the presence of renal disease.
4 more elements
Dependencies are inferred from the claim text.