Back to results
US 6,218,425 B1Granted
8-substituted B-nor-6-Thiaequilenin compounds having activity as selective estrogen receptor modulators
AssigneeEli Lilly and Company
InventorsJeffrey Alan Dodge, Charles Willis Lugar, III
Life of this patent
Estimating the term…
Abstract
Certain B-nor-6-thiaequilenin compounds substituted at the 3-position with hydroxy and at the 8-position with hydroxy or alkoxy of from one to four carbon atoms are selective estrogen receptor modulators and are useful in the treatment of estrogen-related disorders including such conditions as osteoporosis, hyperlipidemia, estrogen-dependent breast cancer, uterine fibrosis, endometriosis, and restenosis.
Claims12
A compound selected from the group consisting of the individual stereoisomers of a compound of the formula
- wherein
- R is hydrogen or straight or branched alkyl of one to four carbon atoms;
- the dotted line represents an optional double bond;
- and
- the parenthetic hydrogen atom is absent when the optional double bond is present.
2 more elements
Dependencies are inferred from the claim text.