3(5)-amino-pyrazole derivatives, process for their preparation and their use as antitumor agents

A method of treating cell proliferative disorders associated with an altered cell dependent kinase activity, comprising:

• administering to a mammal in need thereof an effective amount of a compound represented by formula (I):
• wherein
• R is a C3-C6 cycloalkyl group optionally substituted with a straight or branched C1-C6 alkyl group;
• and
• R1 is a straight or branched C1-C6 alkyl, C2-C4 alkenyl, cycloalkyl, aryl, arylalkyl, arylcarbonyl, aryloxyalkyl or arylalkenyl group, which is optionally substituted with one or more groups selected from the group consisting of cycloalkyl, hydroxy, alkylthio, alkoxy, amino, alkylamino, dialkylamino, alkoxycarbonylamino, alkoxycarbonylalkylamino, alkylcarbonyl, alkylsulphonyl, alkoxycarbonyl, carboxy, halogen, nitro, aryloxy, arylthio, arylsulphonyl, N-alkyl-piperazinyl, piperidinyl, 4-morpholinyl, arylamino, cyano, alkyl, aryl, oxo, haloaryl, haloarylalkyl, haloaryloxy, haloarylsulphonyl, aminosulphonyl, aminocarbonyl, arylcabonyl, perfluorinated alkyl, and perfluorinated alkoxy groups;
• or a pharmaceutically acceptable salt thereof.