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AssigneeAdvanced Monitoring Systems, Inc.
InventorsIrina Even-Tov, Ami Naveh, Igor Kuperman
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A potentiometric method for determining low concentration of an analyte of interest present in a fluid sample in a concentration optionally below its linear range of detection in a presence of at least one interfering substance of known concentration the method is effected by following the steps of (a) adding to the sample a predetermined amount of the analyte of interest, such that a total concentration of the analyte of interest present in the sample is within the linear range of its detection; (b) providing an analyte selective electrode being selective to the analyte of interest and a reference electrode both electrodes being equilibrated with a solution including the at least one interfering substance in concentration similar to said known concentration; (c) contacting the analyte selective electrode and the reference electrode with the sample; (d) measuring a signal representative of a potential drop between the analyte selective electrode and the reference electrode; and (e) using the signal for determining the concentration of the analyte of interest present in the fluid sample prior to the addition of the predetermined amount of the analyte of interest.
A potentiometric method for determining a concentration of an analyte of interest present in a fluid sample in concentration optionally below its linear range of detection, the method comprising the steps of:
A potentiometric method for determining a concentration of an analyte of interest present in a fluid sample in presence of at least one interfering substance of known concentration, the method comprising the steps of:
A potentiometric method for determining low concentration of an analyte of interest present in a fluid sample in a concentration optionally below its linear range of detection in presence of at least one interfering substance of known concentration, the method comprising the steps of:
A device useful in executing a potentiometric method for determining a concentration of an analyte of interest present in a fluid sample in concentration optionally below its linear range of detection by the potentiometric method, the device comprising a container including a predetermined amount of the analyte of interest, such that when the fluid sample is added to the container a total concentration of the analyte of interest present in the sample is within the linear range of its detection.
An electrode equilibrating and maintaining solution useful in equilibrating and maintaining an analyte selective electrode and a reference electrode, said analyte selective electrode and reference electrodes being designed to determine a concentration of an analyte of interest in a fluid sample including a known concentration of at least one interfering substance, the solution having a composition comprising the at least one interfering substance in a concentration similar to said known concentration of the at least one interfering substance in the sample.
A kit useful in executing a potentiometric method for determining low concentration of an analyte of interest present in a fluid sample in a concentration optionally below its linear range of detection by the potentiometric method, the sample including a known concentration of at least one interfering substance, the kit comprising:
Dependencies are inferred from the claim text.